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Sanger Zone - Wellcome Trust Sanger Institute

Question: how do you use computers too look at genome and other thing, because i was wondering how you put information from a biological organism into a computer?

Asked by hgig to Paul on 7 Dec 2011.

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  • Photo: Paul FlicekPaul Flicek answered on 7 Dec 2011:

    DNA can be represented by 4 letters A,C,G,T. These are abbreviations for the chemical compounds that make up the DNA. We can think of the genome as a long string of letters (about 3 billion letters) and we can load this just like a text file.

    The genome is kind of of a book written in a language that we only partly understand. We use computers to help with understanding because they are so much faster at pattern finding. When the computer tells us something, we can often test this in the lab. The lab results might make the computer analysis better.

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